Knockin Services
Negotiable Min Order Quantity Unit
- Required Quantity
-
- Place of Origin
- U.S.A
- Brand name
- Creative Animodel
- Payment Terms
- Negotiable
- Production method
- Negotiable
- Shipping / Lead Time
- Negotiable / Negotiable
- Category
- Pharmaceutical Intermediates
Creative Animodel
- Verified Certificate
-
10
| Product name | Knockin Services | Certification | - |
|---|---|---|---|
| Category | Pharmaceutical Intermediates | Ingredients | - |
| Keyword | gene targeting , custom mouse model , knock in , knock in mouse model | Unit Size | - |
| Brand name | Creative Animodel | Unit Weigh | - |
| origin | U.S.A | Stock | - |
| Supply type | - | HS code | - |
Product Information
Creative Animodel provides a high quality service for the generation of gene-targeted knock-in mouse models. Our team has many years of experience in vector design, ES cell targeting and mouse handling.
Below you will find our different types of Knock-in designs:
- Custom Humanized Mouse Services -This type of mouse models are extensively used as the replacement of in vivo study of human diseases, such as AIDS, cancer, infectious diseases, immune diseases, degenerative diseases, etc. Creative Animodel will deliver its services with the highest possible quality standards, and will make sure the selected customers will be satisfied with the entire process of paid activities
- Point mutant - Introduces a specific point mutation at a specific nucleotide position within the gene of interest. The mutated mouse gene substitutes for the wild type mouse gene while ostensibly preserving the endogenous regulatory regions.
- Inducible point mutant - Introduces a point mutation in a time-controlled manner. This strategy allows the scientists to bypass the limits usually observed with constitutive point mutant such as lethal phenotype, compensatory mechanisms and complex phenotype.
- Reporter/Tag - Introduces a reporter gene such as GFP, lacZ, mCherry, tdTomato, YFP and DsRed into the locus of a target gene in order to monitor the expression of that gene at the transcriptional or translational level. May also be used to monitor protein trafficking.
- Permissive locus (HPRT/Rosa26) - Introduces a safe and targeted insertion of a transgene into the HPRT locus and Rosa26 locus.
Full-Service Knockin Production
Creative Animodel offers a full gene targeting service starting from vector design and construction and finishing with the generation of a targeted mouse line. A fully customized mouse model tailored to your research program will help you achieve your goals.
Secure Confidentiality
Materials and information provided and sent to Creative Animodel are kept private by the strictest security measures. Assay outcomes and experimental data are proprietary to our clients and are also kept confidential. Creative Animodel does not disclose confidential information to third parties unless instructed to do so by the client.
B2B Trade
| Price (FOB) | Negotiable | transportation | - |
|---|---|---|---|
| MOQ | Negotiable | Leadtime | Negotiable |
| Payment Options | Negotiable | Shipping time | Negotiable |
- President
- Mr.Zhang
- Year Established
- 2005
- Company introduction
-
Creative Animodel totally understands that it is a challenging and long-time process to develop novel therapies especially anticancer regimens. As an experienced bioscience CRO, we would like to help you accelerate the process through our preclinical services including PD, PK, toxicology services and the establishment of tumor-bearing animal models, the supply of tumor cell lines and tissues, and the support of tumor related biotechniques.
Our highly experienced preclinical team has performed a huge number of PD, PK, and toxicology experiments to evaluate novel compounds. According to our detailed protocol, specific aspects of drug property and its mechanism of action are fully understood. During researches, the study results will be sent to clients in a timely and cost-effective manner. If necessary, clients can also work with our PD, PK or toxicology team to design the most appropriate protocol and monitor the whole experimental process.
In the past years, Creative Animodel has collected more than 80 cases of human tumors. At present, 30 cases are growing as subcutaneous xenografts in nude mice, and others were retained as nitrogen frozen samples. Tumors types comprise: stomach, lung, liver, pancreas, kidney, bladder, skin, breast, brain, colon, prostate, sarcomas (bone), uterus, ovary and hematological models. Also, we have a full range of human tumor cell lines that have been validated in our in vivo efficacy studies or reported in literature. According to the requirements from clients and our experience, Creative Animodel can offer subcutaneous, orthotopic, metastatic, transgenic and chemoinduced models using these tumor samples and cell lines.
Additionally, Creative Animodel provides powerful tumor-related biotechniques support for clients. Our services focus on in vitro and in vivo preclinical studies as well as toxicological, pathological, and toxicokinetics researches.
Creative Animodel has constructed systematic data and experience in pharmacology or oncology services. If you are interested in our laboratory, please contact us. Our research scientists will work closely with you to develop detailed study protocols to meet your goals.
- Main Markets
-
Australia
Canada
Singapore
South Korea
U.S.A
- Main Product
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