PROTIA Allergy-Q 128M is a cutting-edge multiplex diagnostic kit designed to detect and evaluate 117 specific allergens, including total IgE, in a single test. This innovative solution provides a reliable and efficient method for diagnosing atopic allergy, a hypersensitive immunological condition mediated by immunoglobulin E (IgE) antibodies. Allergens stimulate lymphocyte B cells to produce IgE, which binds to mast cells or basophilic leukocytes. Upon re-exposure to the allergen, this triggers cell degranulation, releasing vasoactive amines that cause symptoms such as hay fever, asthma, dermatitis, hives, and anaphylactic shock. Assessing IgE levels is essential for precise diagnosis and effective management of these conditions.

The PROTIA Allergy-Q 128M uses enzyme immunoassay principles, incorporating nitrocellulose membranes with allergens adsorbed at regular intervals. These membranes are organized into a single plastic panel, enabling simultaneous testing of dozens of allergens. Allergen-specific IgE antibodies bind to antigens on the membrane, followed by binding to biotin-coupled anti-human IgE antibodies. The biotin is captured by streptavidin conjugated with alkaline phosphatase, and a substrate reaction produces a color gradient from light purple to dark purple. This color intensity, proportional to IgE concentration, is analyzed using a precise color-measuring device.

With its ability to process a wide range of allergens in one test, PROTIA Allergy-Q 128M provides an advanced, comprehensive, and user-friendly approach to allergy diagnosis.

Key Features of PROTIA Allergy-Q 128M

• Comprehensive Allergen Detection: Detects 117 specific allergens and total IgE in a single test.
• Efficient Multiplex Testing: Features four nitrocellulose membranes on a single panel, enabling simultaneous evaluation of multiple allergens.
• Accurate IgE Quantification: Based on enzyme immunoassay (EIA) principles, ensuring precise and reliable measurement of allergen-specific IgE.
• Color-Based Quantitative Analysis: Produces a gradient color change from light purple to dark purple proportional to IgE concentration, analyzed using a color-measuring device.
• User-Friendly and Reliable: Provides comprehensive allergy information in one test, streamlining the diagnostic process.
• Supports Diagnosis of Various Clinical Symptoms: Suitable for assessing conditions such as hay fever, asthma, dermatitis, hives, and anaphylactic shock.
• Advanced Technology: Utilizes streptavidin-alkaline phosphatase and biological reactions for high sensitivity and specificity.