H201 peptide is a novel, 10-amino acid peptide from amino acid sequence of highly conserved human Copine protein family (specifically, CPNE7), which activates periodontal ligament fibroblasts (PDL fibroblasts) to generate periodontal ligament and cementum regeneration.

1. The periodontal ligament (PDL) is a connective tissue located between the cementum and the alveolar bone.
2. The most unique function of the PDL is to provide attachment of the teeth to the surrounding alveolar bone to support or resist mechanical forces.
3. But once the periodontal ligament (PDL) is damaged, it is difficult to regenerate its characteristic structure

KH201 peptide activates periodontal ligament fibroblast activation which induces:
1. Periodontal ligament regeneration & functional alignment
2. Re-adhesion to cementum & alveolar bone
3. Restoration & maintenance of periodontal tissue & tooth function