KH001 - Dentin hypersensitivity
1. When dentinal tubules are exposed, odontoblasts in the dentinal tubules come into contact with external stimuli, such as hot or cold temperature and pressure. This contact triggers pulp nerves and leads to sharp pain known as dentin hypersensitivity.
2. Activated odontoblasts secrete dentin matrix to the intratubular dentinal tubules and occlude them. As a result, the dentin is restored back to its original state. This is the world’s first hypersensitivity treatment using HysensBio’s physiologic dentin regeneration.
3. Pre-existing treatments were to externally block the dentinal tubules using nonphysiologic dentin materials. In this case, outward hydrostatic pressure in the dentinal tubules causes the restorative materials to fall out.
4. However, treatment with Selcopintide regenerates the native dentin layer, filling in the exposed area and withstanding the pressure. Using this technology, we believe it is possible to fundamentally treat dentin hypersensitivity.