Appearance information

Appearance: Colorless and transparent vial injection containing colorless and transparent liquid

Ingredient information

Sodium Selenite Pentahydrate 0.166mg/mL

storage method

Sealed container, 1~30℃, shaded storage

Efficacy effect

Selenium supplementation in patients with selenium deficiency that cannot be supplemented by nutritional supplementation

dosage

As selenium, 100 μg per day is injected intramuscularly or intravenously. If necessary, the dose can be increased to 200 μg per day.

Blood levels of selenium should be measured to determine if treatment is appropriate.

If this drug is additionally administered to the basic TPN injection, the daily dose must be 100 μg as selenium.

Precautions for use

1. Warning

Do not use in selenium poisoning patients with selenium toxicity.

2. Do not administer to the following patients.

Patients with hypersensitivity to this drug or its components

3. Adverse reactions

1) There have been very rare reports of pain and allergic reactions when injecting this drug.

2) If symptoms such as dermatitis, sweat/respiratory odor, hair loss, impatience, and vomiting appear

4. General notes

1) When using this drug by mixing it with other drip intravenous solutions, care should be taken not to form a precipitate. Selenium may precipitate when the pH of the solution drops below 7.0 or when mixed with a reducing agent such as vitamin C. Selenium is insoluble in aqueous solutions, so it is not used by the body.

2) When mixing this drug with other drugs, you must check whether a precipitate is formed for safety, and if a precipitate is formed or the color changes, do not use this drug.

3) Since this drug contains sodium, this should be considered in patients who need to adjust a low-salt diet.

5. Administration to pregnant and lactating women

1) Clinical trials for pregnant women have not been conducted, and there is a report that high-concentration selenium administration caused fetal malformations in animal experiments. When administered to women who are pregnant or who may become pregnant, administer this medicine only when the therapeutic benefits are judged to outweigh the risks.

2) Selenium is found in breast milk in the form of selenium protein and selenium enzyme, but the safety of this drug for nursing mothers has not been established. .

6. Treatment in case of overdose

In case of overdose, acute symptoms may include garlic smell from the mouth, fatigue, nausea, diarrhea and abdominal pain. In addition, chronic overdose can affect the growth of nails and hair, and can lead to polyneuropathy of peripheral nerves.

In case of overdose, perform gastric lavage, induce urination, or take a high dose of vitamin C. In case of extreme overdose (1,000 to 10,000 times the normal dose), selenium must be removed by dialysis. At this time, dimercaprol (dimercaprol) should not be used because it can increase the toxicity of selenium.

7. Precautions for storage and handling

1) Keep out of reach of children.

2) Store this drug at room temperature in a dry place in a packaged state (shielded).

3) This medicine should be used immediately after opening.

4) Be aware that changing to another container can cause an accident or is undesirable in terms of quality maintenance.

Appearance information

Appearance: Colorless and transparent vial injection containing colorless and transparent liquid

Ingredient information

Sodium Selenite Pentahydrate 0.166mg/mL

storage method

Sealed container, 1~30℃, shaded storage

Efficacy effect

Selenium supplementation in patients with selenium deficiency that cannot be supplemented by nutritional supplementation

dosage

As selenium, 100 μg per day is injected intramuscularly or intravenously. If necessary, the dose can be increased to 200 μg per day.

Blood levels of selenium should be measured to determine if treatment is appropriate.

If this drug is additionally administered to the basic TPN injection, the daily dose must be 100 μg as selenium.

Precautions for use

1. Warning

Do not use in selenium poisoning patients with selenium toxicity.

2. Do not administer to the following patients.

Patients with hypersensitivity to this drug or its components

3. Adverse reactions

1) There have been very rare reports of pain and allergic reactions when injecting this drug.

2) If symptoms such as dermatitis, sweat/respiratory odor, hair loss, impatience, and vomiting appear

4. General notes

1) When using this drug by mixing it with other drip intravenous solutions, care should be taken not to form a precipitate. Selenium may precipitate when the pH of the solution drops below 7.0 or when mixed with a reducing agent such as vitamin C. Selenium is insoluble in aqueous solutions, so it is not used by the body.

2) When mixing this drug with other drugs, you must check whether a precipitate is formed for safety, and if a precipitate is formed or the color changes, do not use this drug.

3) Since this drug contains sodium, this should be considered in patients who need to adjust a low-salt diet.

5. Administration to pregnant and lactating women

1) Clinical trials for pregnant women have not been conducted, and there is a report that high-concentration selenium administration caused fetal malformations in animal experiments. When administered to women who are pregnant or who may become pregnant, administer this medicine only when the therapeutic benefits are judged to outweigh the risks.

2) Selenium is found in breast milk in the form of selenium protein and selenium enzyme, but the safety of this drug for nursing mothers has not been established. .

6. Treatment in case of overdose

In case of overdose, acute symptoms may include garlic smell from the mouth, fatigue, nausea, diarrhea and abdominal pain. In addition, chronic overdose can affect the growth of nails and hair, and can lead to polyneuropathy of peripheral nerves.

In case of overdose, perform gastric lavage, induce urination, or take a high dose of vitamin C. In case of extreme overdose (1,000 to 10,000 times the normal dose), selenium must be removed by dialysis. At this time, dimercaprol (dimercaprol) should not be used because it can increase the toxicity of selenium.

7. Precautions for storage and handling

1) Keep out of reach of children.

2) Store this drug at room temperature in a dry place in a packaged state (shielded).

3) This medicine should be used immediately after opening.

4) Be aware that changing to another container can cause an accident or is undesirable in terms of quality maintenance.