Dimethyl fluoromalonate

Dimethyl fluoromalonate


Negotiable Min Order Quantity Unit

Required Quantity
Place of Origin
China
Brand name
BGT
Payment Terms
L/C,T/T
Production method
Negotiable
Shipping / Lead Time
Negotiable / Negotiable
Keyword
pharmaceutical intermediate, dimethyl fluoromalonate, dimethyl 2-fluoromalonate, 344-14-9
Category
Organic Intermediate , Pharmaceutical Intermediates

Banff Green Technologies, Inc.

Membership
BIZ
Country / Year Established
China China / 2014
Business type
Manufacturer
Verified Certificate

7

Product name Dimethyl fluoromalonate Certification -
Category Organic Intermediate
Pharmaceutical Intermediates
Ingredients -
Keyword pharmaceutical intermediate , dimethyl fluoromalonate , dimethyl 2-fluoromalonate , 344-14-9 Unit Size -
Brand name BGT Unit Weigh 300000 kg
origin China Stock -
Supply type - HS code -

Product Information

 

What is Dimethyl Fluoromalonate?

Dimethyl fluoromalonatenate, CAS number 344-14-9, is an organic intermediate widely used in the fields of pharmaceuticals, agricultural chemicals, materials, dyestuff, industrial additives, etc. It is also known as 2-fluoro-malonic acid dimethyl easter; 2-fluoro-4-methoxyacetoacetic acid methyl ester; Butyric acid, 2-fluoro-3-oxo-4-methoxy-, methyl ester; Dimethyl 2-fluoromalonate; Methyl 2-fluoro-4-methoxyacetoacetate; Fluoro-malonicaciddimethylester, etc.

 

Key applications of Dimethyl fluoromalonatenate

The already known key applications of Dimethyl fluoromalonatenate include: used as pharmaceutical intermediate, in synthesizing fungicides, special materials, dyestuff, enzyme inhibitors, fluoride-containing amino acids, fluoride-containing Chalcone, sedative, etc. The research and industrialization of Dimethyl fluoromalonatenate is still at the beginning stage, and more applications will be explored in the future. 

 

Dimethyl fluoromalonatenate as pharmaceutical intermediate

Dimethyl fluoromalonatenate has been shown to be a valuable intermediate in the synthesis of alpha-fluoroalkanoic acids, including y-fluoroglutamic acid. It is also an intermediate for 5-Fluoropyrimidine (CAS 675-21-8) compounds, which shows good bioactivities for anti-cancer, antibacterial effects.

 

Dimethyl fluoromalonatenate used in agricultural chemical industry

Dimethyl fluoromalonatenate is an important intermediate for the synthesis of environment-friendly fungicide Fluoxastrobin developed by Bayer CropScience in 2005. Fluoxastrobin, commonly used  in Fandango, Fortix, Scenic, DISARM, EVITO, and HEC 480 SC (trade names), is a new strobilurin fungicide active ingredient for the control of fungal diseases such as early blight, late blight, leaf spots, leaf rust, and Rhizoctonia solani.

 

Dimethyl fluoromalonatenate for special materials

New functional fluorinated materials are rapidly emerging to meet the demanding requirements of advanced applications in fields as diverse as sensing, catalysis and environmental protection due to its excellent prosperities such as chemical resistance, heat endurance, dielectricity, noninflammability, non-stick performance and wear-resistance. AS per Journal of Materials Chemistry, fluororesin, fluoroelastomers, and fluorosilicone (FRS) are very popular fluoride-containing materials widely used in the fields of photoelectrons, fiber optic, etc. Dimethyl fluoromalonatenate can be used as the starting material for many of these specialty materials.

 

Dimethyl fluoromalonatenate in synthesizing 4,5,6-Trifluoropyrimidine and dyestuff

More information is to be updated for the mechanism of action of Dimethyl fluoromalonatenate for the preparation of 4,5,6-Trifluoropyrimidine (CAS 17573-78-3). 4,5,6-Trifluoropyrimidine is an important pesticide intermediate and it is also applied as an intermediate dye industry. 

 

Dimethyl fluoromalonatenate in preparing enzyme inhibitors

According to Wikipedia, fluoride salts are commonly used in biological assay processing to inhibit the activity of phosphatases, such as serine/threoninephosphatases. Fluoride mimics the nucleophilic hydroxide ion in these enzymes' active sites.Beryllium fluoride and aluminium fluoride are also used as phosphatase inhibitors, since these compounds are structural mimics of the phosphate group and can act as analogues of the transition state of the reaction. Dimethyl fluoromalonatenate can be used to various synthesize enzyme inhibitors.

 

Dimethyl fluoromalonatenate can also be used to prepare fluoride-containing amino acids, fluoride-containing Chalcone, fluorotetrahydroquinolines, and sedative areas.

 

Our advantages:

 

Environmental friendly and risk free

Our novel manufacturing process is much more environmental friendly than the traditional process. The traditional process emits HF which is extremely toxic and corrosive and a mixture of methylbenzene and triethylamine which are also toxic and difficult to contain. In contrast, our process does not involve any of these materials. Thus, our wastes can be easily treated and reach the emission standard.

 

Higher purity

Our Dimethyl fluoromalonatenate can reach as high as 99% purity (by GC), and is the highest assay that is commercially available. The common purity of Dimethyl fluoromalonatenate on the market is about 90% and it is difficult to further purify.

 

Bulk stock

As Dimethyl fluoromalonatenate is one of Banff’s most important products, a large stock is available all year round.

 

If you need quotation or price for Dimethyl fluoromalonatenate, please kindly send inquiry to us. Information as MSDS, COA, GC and NMR spectrum are all available upon your request.

 

B2B Trade

Price (FOB) Negotiable transportation -
MOQ Negotiable Leadtime Negotiable
Payment Options L/C,T/T Shipping time Negotiable

Banff Green Technologies, Inc.

Country / Year Established
China China / 2014
Membership
BIZ
Business type
Manufacturer

7

President
Xue Yang
Address
Floor 29, CapitaMalls Plaza, No. 6088 Humin Rd., Minhang Dist.
Product Category
Antibiotic and Antimicrobial Agents,Inorganic Salts,Organic Intermediate,Pharmaceutical Intermediates
Year Established
2014
No. of Total Employees
101-500
Company introduction

 

Banff Green Technologies, Inc. is a technologically innovative company that focuses on chemicals, materials, pharmaceuticals, crop science and environmental technology. The company headquarter is based in Shanghai, China. Our research and development team is comprised of a talented and experienced team of PhD’s with strong scientific backgrounds dedicated to our mission. We are also supported by strong infrastructure, which include state of the art lab facilities, two pilot facilities and seven manufacturing sites located in five provinces in China.

Our core businesses span over the following areas: R & D, production and sales of fine and specialty chemicals, contract manufacturing services and custom synthesis. 
Our main products are: fluorinated fine chemicals (mainly Diethyl fluoromalonate and dimethyl fluoromalonate), D-p-Methyl Sulfone Phenyl Ethyl Serinate, Florfenicol, D-(-)-threo-2-Amino-1-(4-nitrophenyl)-1,3-propanediol, and chloramphenicol).

Our corporate mission is to achieve environmental protection and sustainability while being socially responsible through our research and innovation. We sincerely hope to better serve our customers through every facets of their needs and together we can achieve a more sustainable future.
Main Product

Related Products

Other buyers also search

Membership Grade

BUYER

Biz Pro VIP

SELLER

Biz Pro VIP
팝업닫기
Live Chat A new message arrives
from a business partner.

No Data

  • There is no data to load
  • Check out the My TK > My Inquiries list.
  • After agreeing to the use of the Live Chat service, the list is printed only when there is at least one history of receiving or sending a Live Chat request.

If you have not yet agreed to use the Live Chat service,

You can use the Live Chat freely after agreeing to the use of the Live Chat service.

View more
View more