A tea made of the vine is used for diabetes, hypertension, worms, dysentery, malaria and as a general tonic and blood purifier. It is also very effective to relieve constipation and colds and fevers in children.

Women in Latin American use the leaf for menstrual problems to promote discharge after childbirth.

The tea is taken for 9 days after giving birth to clean out and tone up all the organs involved in the delivery. Cerasee is also used as a natural method of birth control, by taking two cups each day after intercourse, for three days. It is said that women who drink Cerasee daily will not conceive during that time. As a wash, the tea is used externally for sores, rashes, skin ulcers and all skin problems. A Cerasee bath is good for arthritis, rheumatism, gout and other similar ailments.

Today folks in the Caribbean still use cerasee as a blood cleanser; bush bath for beautiful skin; and for diabetes, cancer and other infectious diseases. We also use it for all types of stomach complaints including griping or pain in the stomach, amoebas and intestinal parasites and as a laxative. Research confirms these benefits by documenting the anti-bacterial and anti-parasitic properties within cerasee.

Cerasee has been used in various Asian and African traditional medicine systems for a long time. In Turkey it has been used as a folk remedy for a variety of ailments, particularly stomach complaints. The fruit is broken up and soaked in either olive oil or honey.The plant contains several biologically active compounds, chiefly momordicin I and II, and cucurbitacin B.

The plants contains also several bioactive glycosides (including momordin, charantin, charantosides, goyaglycosides, momordicosides) and other terpenoid compounds (including momordicin-28, momordicinin, momordicilin, momordenol, and momordol). It also contains cytotoxic (ribosome-inactivating) proteins such as momorcharin and momordin.

Diabetes:

                       In 1962, Lolitkar and Rao extracted from the plant a substance, which they called charantin, which had hypoglycaemic effect on normal and diabetic rabbits. Another principle, active only on diabetic rabbits, was isolated by Visarata and Ungsurungsie in 1981. Cerasee has been found to increase insulin sensitivity. In 2007, a study by the Philippine Department of Health determined that a daily dose of 100 mg per kilogram of body weight is comparable to 2.5 mg/kg of the anti-diabetes drug glibenclamide taken twice per day. Tablets of Bitter Melon extract are sold in the Philippines as a food supplement and exported to many countries.Other compounds in Cerasee have been found to activate the AMPK, the protein that regulates glucose uptake (a process which is impaired in diabetics).

  Cerasee also contains a lectin that has insulin-like activity due to its non-protein-specific linking together to insulin receptors. This lectin lowers blood glucose concentrations by acting on peripheral tissues and, similar to insulin's effects in the brain, suppressing appetite. This lectin is likely a major contributor to the hypoglycemic effect that develops after eating Bitter Melon.

Anti malarial:

 Cerasee is traditionally regarded in Asia as useful for preventing and treating malaria. Tea from its leaves is used for this purpose also in Panama and Colombia. In Guyana, Cerasee are boiled and stir-fried with garlic and onions. This popular side dish known as corilla is served to prevent malaria. Laboratory studies have confirmed that species related to Cerasee have anti-malarial activity, though human studies have not yet been published.

Anti Cancer:

                     Researchers at Saint Louis University claims that an extract from Cerasee, commonly eaten and known as karela in India, causes a chain of events which helps to kill breast cancer cells and prevents them from multiplying.

Cerasee has been used in traditional medicine for several other ailments, including dysentery, colic, fevers, burns, painful menstruation, scabies and other skin problems. It has also been used as abortifacient, (no ideas please) for birth control, and to help childbirth.

Anti viral:                

In Togo the plant is traditionally used against viral diseases such as chickenpox and measles. Tests with leaf extracts have shown in vitro activity against the herpes simplex type 1 virus, apparently due to unidentified compounds other than the momordicins.               

Laboratory tests suggest that compounds in Cerasee might be effective for treating HIV infection. As most compounds isolated from Cerasee that impact HIV have either been proteins or lectins, neither of which are well-absorbed, it is unlikely that oral intake of Cerasee will slow HIV in infected people. It is possible oral ingestion of Cerasee could offset negative effects of anti-HIV drugs, if a test tube study can be shown to be applicable to people.

Cardio protective:

   Studies in mice indicate that Cerasee seed may have a cardio protective effect by down-regulating the NF-κB inflammatory pathway.

Cerasee has been used in traditional medicine for several other ailments, including dysentery, colic, fevers, burns, painful menstruation, scabies and other skin problems. It has also been used as abortifacient, for birth control, and to help childbirth.