PolyBone Beta-tricalcium Phosphate Bone Graft Substitute 

OVERVIEW 

PolyBone® is a synthetic, osteoconductive, osteoinductive, resorbable calcium phosphate bone substitute that can replace or supplement autogenous bone. PolyBone® eliminates the need for autologous bone harvesting, thus reducing overall patient morbidity.

PolyBone® is manufactured in a cleanroom environment from a biocompatible, beta-tricalcium phosphate (β-TCP). This material contains two of the main mineral constituents of bone, calcium and phosphate. Replaced with bone in 6-18 months, PolyBone® is ideal for many bone void filler applications.

PolyBone®’s bone formation mechanism is promoted by polyphosphate ingredient that activates BMP, accelerating bone regeneration. This mechanism will achieve the best results in a variety of surgeries involving bone fracture, craniofacial surgery, spine plasty, oral surgery, etc.

With its synthetic manufacturing process, PolyBone® shows reliable and standardized biomechanical properties. The compressive strength of PolyBone® is similar to that of human cancellous bone.

FEATURES & BENEFITS

• Osteoconductivity provides a scaffold for bony ingrowth, giving bone cells a path upon which to lay down new host bone.

• Fully synthetic without any risk of disease transmission by allograft and autograft, PolyBone® gives surgeons and patients peace of mind.

• Macropores of 100 µm-500 µm creates optimal environment for vascularization and bony infiltration, promoting bone formation throughout the entire implant, not just at the periphery.

• Micropores of less than 10 µm increases surface area where new bone forms and allows circulation of fluids throughout the implant.

• Resorption rate in 6-18 months is similar to the regeneration of new bones.

• Mixed with blood and bone marrow aspirate, PolyBone® increases biological activity at defect site.

• Porosity of 60-70% provides optimal structure for bone ingrowth without loss of stability.

PRODUCT TYPES

• Powder

• Granule

• Block  

INDICATIONS FOR USE

1. Neurosurgery

• Repair of neurosurgical burr holes, craniotomy cuts and other cranial defects

• Restoration or augmentation of bony contour in the craniofacial skeleton

• Augmentation and smoothing contour of skeletal irregularities

2. Spine & Orthopaedic surgery

• Filler for bony voids, gaps of the skeletal system, or defects that are not intrinsic to the stability of bony structure in the extremities, spine and pelvis

• Treatment of surgically or traumatically created osseous defects

• Packed or placed into the site and may be combined with autogenous blood, bone marrow or saline

• Bone filler for revision of the artificial hip joint, knee joint, shoulder joint and other joints

3. Dental surgery

• Treatment of periodontal bone for dentate substitution surgery