Rosuvastatin calcium CAS No.: 147098-20-2

Rosuvastatin calcium CAS No.: 147098-20-2


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Place of Origin
Brand name
366
Payment Terms
Negotiable
Production method
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Shipping / Lead Time
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Keyword
cardiovascular, rosuvastatin, rosuvastatin calcium, 147098-20-2
Category
Pharmaceutical Intermediates
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366 Pharma (Nanjing) Co., Ltd.

Country / Year Established
China China /
Business type
Others
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Product name Rosuvastatin calcium CAS No.: 147098-20-2 Certification -
Category Pharmaceutical Intermediates Ingredients -
Keyword cardiovascular , rosuvastatin , rosuvastatin calcium , 147098-20-2 Unit Size -
Brand name 366 Unit Weigh -
origin Stock -
Supply type - HS code -

Product Information

Physical and Chemical Properties

Common Name

Rosuvastatin calcium

Chemical Name

 

Molecular Formula 

C44H54CaF2N6O12S2

Molecular Weight    

1001.14

CAS No.

147098-20-2

EINECS No.

 

 

Product Specification

Appearance

White or yellow powder

Purity

98.0%

Shelf life

2 years

Quality Standard

In-house

Certification

In process of applying for GMP and ISO 9001

 

Product Description

Rosuvastatin is a member of the drug class of statins, used to treat high cholesterol and related conditions, and to prevent cardiovascular disease.

Rosuvastatin was initially developed by Shionogi in the late 1980s; the original development number is S-4522. In June, 1998, the development, market and sales rights were in-licensed to AstraZeneca. Rosuvastatin was approved for the first time in Holland on November 7, 2002, and then was approved in Canada in Feb, 2003. Approval in the United States by the FDA came on August 12, 2003.

Rosuvastatin is a competitive inhibitor of the enzyme HMG-CoA reductase, having a mechanism of action similar to that of other statins. Its approximate elimination half life is 19 hours and its time to peak plasma concentration is reached in 3–5 hours following oral administration.

We manufacture and supply APIs and relative intermediates of Statin series for cardiovascular disease, including Pitavastatin, Rosuvastatin, Atorvastatin and Fluvastatin.

TECHNICAL DATA SHEET

Item

Specification 

Appearance

White to yellow powder

Identification

IR-Spectrum

UV

Calcium content

3.5%-4.5%

Water

≤5.0%

Specific Rotation

14.0-20.0

Heavy Metals

≤0.002%

Relative Substance

Diastereomer                      ≤0.30%

Rosuvastatin lactone          ≤0.20%

Diene                                    ≤0.30%

Unknown single impurity     ≤0.20%

Total impurity                        ≤1.0%

Assay (On dry basis)

98.0-102.0%

 

Packaging & Shipping

Packaging Spec.

1kg/bag, 25kg/drum

Shipping Mode

Air or express

Loading Port

Nanjing, Shanghai or other China main ports

Delivery Time

Depending upon the order volume

 

Payment

Payment Mode

T/T, L/C, D/P, D/A and others

Note: For small value order, we always require 100% T/T in advance as payment term.

B2B Trade

Price (FOB) Negotiable transportation -
MOQ Negotiable Leadtime Negotiable
Payment Options Negotiable Shipping time Negotiable

366 Pharma (Nanjing) Co., Ltd.

Country / Year Established
China China /
Business type
Others

13

President
Betty Bi
Address
80 Yunlongshang Road, Nanjing, Jiangsu 210019, China
Product Category
Food Additives,Pharmaceutical Intermediates
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