Sodium Hyaluronate

Cas No. :9067-32-7

Specs:cosmetic grade, pharm grade, food grade
Sodium Hyaluronate, hyalurionic acid EP4.0 

Available molecular weight

1.> 2000,000Dalton

2.1500,000~2000,000 Dalton

3.1000,000~1500,000 Dalton

4.500,000~1000,000 Dalton

5.100,000~500,000 Dalton

6.10,000~100,000 Dalton

7.< 10000 Dalton

Application in the field of cosmetic The amount of the additive HA in cosmetic is about 0.1%, and in special use its amount can be up to 0.5%. Higher molecular HA can be used in anti-wrinkle and sun-block creams, and its amount is about 0.1%~0.5%. Due to its good penetration, lower molecular HA is widely used in cosmetic, and the amount of which is usually about 0.1%. For effective products such as sun-block and sun-screen the recommended HA amount is more than 0.1%. HA can improve efficiency and prolong the expiration as its excellent sustained-release.

Product functions

Attention In order to improve the velocity of HA solubility, a small amount of alcohol can be used to make it infiltrate. There is no influence on process of ingredients as alcohol will volatilize.

Use Additions: The amount can be determined after sample test, generally 0.2~1.0% (relative finished products usage) according to different varieties. HA can be used separately with other moisturizing factors.

Dissolve:In order to make HA dissolve easily, the preservatives in the HA production are added in purified water to make HA immerse in mixing state. HA should be immersed absolutely to make its water absorption swelling to fully gel, and then mixing about 0.5h to dissolve. Heating can improve the dissolution rate, and the temperature is not more than 60℃, 40~50℃ advisable. For emulsified cosmetics, HA solution can be somewhat as the water phase emulsified with oil, for non-emulsified cosmetics, HA can be mixed with other components directly.

Application in the field of health food HA is widely used in health food in western countries. At home and abroad health food(nutrition food )manufacturers often choose HA(800,000~1200,000Dalton) as additives to produce capsules and tablets. Low molecular weight HA is often added in oral liquid, oral powder and soft capsule due to its advantages such as good solubility, uniform mixture and excellent absorption.

Oral security and bioavailability When taken orally the concentration of HA in blood begins to increase rapidly after four hours, after twelve hours the HA concentration can get the maximum. When HA is continuously taken for 7 days, the HA concentration can keep steady.

Application in the field of medicine HA can be used as viscoelastic agent in eye intraocular lens implant surgery, as filling agent in osteoarthritis and rheumatoid arthritis and other joint operation, as medium in eye drops and the prevention of postoperative adhesion and promoting the healing of skin wound, etc. HA with other drugs can act synergistically in drug slow release process, can play an important role in controlled drug release.