Category   Inhibitor

Product Name                 Naphthoquine phosphate

Catalog Number                       173531-58-3

Synonyms        Naphthoquine phosphate

Purity>98%

CAS Number173531-58-3

Target          Antiparasitic

Description

Naphthoquine phosphate and artemisinine are two antimalarials developed in China. Both drugs have proven to be efficacious and well tolerated as monotherapy as well as in combination in patients suffering from malaria. The Co-naphthoquine, a novel antimalarial combination, is an oral fixed combination tablet of the naphthoquine phosphate and artemisinine. Artemisinin is characterised by a rapid onset of schizonticidal action and a short half-life. Parasite clearance is, however, often incomplete when it is employed as a single agent unless high dosages are used over several days, but such a regimen may reduce patient compliance and increase the danger of toxicity. Naphthoquine phosphate, by contrast, has a slower onset of action and a longer half-life, associated with a low recrudescence rate.

Molecular Formula        C24H34ClN3O9P2

Molecular Weight       605.94