HE4 (Human Epididymis Protein 4)

HE4 (Human Epididymis Protein 4)


Negotiable Min Order Quantity Unit

Required Quantity
Place of Origin
China
Payment Terms
Negotiable
Production method
Negotiable
Shipping / Lead Time
Negotiable / Negotiable
Keyword
diagnostic reagent, cancer diagnosis, tumor marker
Category
Medical Devices

Tellgen corporation

Membership
BIZ
Country / Year Established
China China / 2003
Business type
Manufacturer
Verified Certificate

9

Product name HE4 (Human Epididymis Protein 4) Certification -
Category Medical Devices Ingredients -
Keyword diagnostic reagent , cancer diagnosis , tumor marker Unit Size -
Brand name - Unit Weigh -
origin China Stock -
Supply type - HS code -

Product Information

 

HE4 (Human Epididymis Protein 4)

Compatible instrument: Luminex 200,TESMI F4000 .

Reference Value: Females: < or =140 pmol/L

Tellgen also provide following Tumor markers and Tumor Marker control :

CA125

CA153

CA24-2

CYFRA21-1

AFP

CEA 

CEA

total PSA

free PSA

free-beta-hCG

CA19-9

NSE

SCCA

CA72-4

CA50

HE4

ProGRP

PGI/PGII

Control 1

Control 2

Control 3

 

Increase in human epididymis protein 4 (HE4) suggests recurrence or disease progression, while a decrease suggests therapeutic response. A change in serum HE4 concentration of > or =20% is considered significant.

 

Human epididymis protein 4 (HE4) belongs to the family of whey acidic four-disulfide core proteins. Currently, the biologic function of HE4 is unknown.

 

HE4 has been shown to be overexpressed in 93% of serous, 100% of endometrioid, and 50% of clear cell ovarian carcinomas. In a study of 233 patients with a pelvic mass, including 67 with epithelial ovarian cancer, HE4 had a higher sensitivity for ovarian cancer detection than cancer antigen 125 (CA 125), 72.9% versus 43.3%, respectively, at a specificity of 95%. Researchers also found HE4 to be elevated in more than half of the ovarian cancer patients who did not have elevated CA 125 levels; therefore, the combination of markers provided slightly improved cancer diagnostic sensitivity for the detection of ovarian cancer.

 

The main established application of HE4 is in post-therapy monitoring of ovarian cancer patients, who had elevated pretreatment levels. In this setting, it complements CA 125 measurement and facilitates follow-up of patients with little or no CA 125 pretreatment elevations.

 

Certain histological types of ovarian cancer (mucinous or germ cell tumors) rarely express HE4, therefore the use of HE4 is not recommended for monitoring of patients with these types of ovarian cancer.

 

 

 

B2B Trade

Price (FOB) Negotiable transportation -
MOQ Negotiable Leadtime Negotiable
Payment Options Negotiable Shipping time Negotiable

Tellgen corporation

Country / Year Established
China China / 2003
Membership
BIZ
Business type
Manufacturer

9

President
Yao Jiaoer
Address
Building 1, No.115, Lane 572, Bibo road, Free trade area
Product Category
Other Monitoring & Diagnostic Equipment
Year Established
2003
No. of Total Employees
101-500
Company introduction

Shanghai Tellgen Corporation. was founded in 2003 and dedicated exclusively to the development, production and distribution of high-quality automated workflow solutions for research and clinical diagnostics laboratories in the life sciences sector. With the tremendous development, Tellgen became the the market leader in moleucular diagnosis area, and had consistently delivered series diagnostic products for healthcare 

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