Sample preparation is critical for proteomics analysis, and Creative Proteomics provides sample preparation service according to your needs.

Proteomics aims to study dynamically changing proteins expressed by a whole organism, specific tissue or cellular compartment under certain conditions. Consequently, two main goals of proteomics research are to identify proteins derived from complex mixtures extracted from cells, and to quantify expression levels of those identified proteins.

Each of these protein sources is comprised of many more components than the proteins themselves, these non-protein sources include nucleic acids, lipids, sugars, and a wide variety of small molecules. Furthermore, unlike DNA and RNA, both of which are chemically homogeneous, proteins are very heterogeneous and vary widely with respect to their size, charge, hydrophobicity, and structure. In addition, many proteins undergo post-translational modification and may have a variety of non-peptide moieties bound to them. This chemical heterogeneity makes isolating proteins extremely challenging.