The Plasmodium Lactate Dehydrogenase (pLDH) is an oxidoreductase. It is the last enzyme of the glycolytic pathway, essential for ATP generation, and one of the most abundant enzymes expressed by P.falciparum. pLDH does not persist in the blood but clears about the same time as the parasites when treated successfully. The lack of antigen persistence after treatment makes the pLDH test useful in predicting treatment failure. pLDH from P.vivax, P.ovale or P.malariae exhibits 90-92% identity to pLDH from P.falciparum.

One Step Malaria Ag Pf/Pv (pLDH/pLDH) Test qualitatively analyzes Plasmodium falciparum and Plasmodium vivax antigens in whole blood using immunochromatography. The target antigen is Histidine-Rich Protein II (HRP-II) of Plasmodium faciparum and plasmodium lactate dehydrogenase (pLDH) of Plasmadium vivax, and the screening test result can be obtained within 25 minutes with its high sensitivity and specificity.